benzodiazepine相关论文
Beneficial effects of benzodiazepine diazepam on chronic stress-induced impairment of hippocampal st
Whether benzodiazepines (BZD) have beneficial effects on the progress of chronic stress-induced impairment of hippocampa......
Global health is increasingly being threatened by the rapid emergence of drug-resistant microbes....
OBJECTIVE To identify benzodi⁃azepine(BZD)effects that are insensitive to the classical BZD binding site antagonist,flu......
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Test of the Popular Benzodiazepine Alprazolam in a Positive Conditioned Place-Preference Model in Fe
<span lang="EN-US" style="white-space:normal;font-family:Verdana;">The benzodiazepines were introduced into medical prac......
１ＩＮＴＲＯＤＵＣＴＩＯＮＢｅｎｚｏｈｅｔｅｒｏａｚｅｐｉｎｅｃｏｍｐｏｕｎｄｓａｒｅｉｍｐｏｒｔａｎｔｐｈａｒｍａｃｅｕｔｉｃａｌａｇｅｎｔｓ〔１，２〕．Ｉｎｒｅｃｅｎｔｙｅａｒｓ，ｉｔｈａｓｂｅｅｎｆｏｕｎｄｔｈａｔｂｅｎｚｏｈｅｔｅｒｏａｚｅ.........
目的:评估临床药师实施干预措施对降低苯二氮(艹卓)类药用量的效果.方法:临床药师为重复应用苯二氮(艹卓)类药3个月以上的成年患者......
目的 建立可同时测定血清中4种苯二氮茧类药物浓度的HPLC-DAD方法,并将该方法应用于心身科患者的血药浓度测定.方法 色谱柱:C18色......
Syntheses and Crystal Structures of Pyridyl Substituted Dibenzo[b,e]-[1,4]diazepin-1-one Derivatives
本文通过对荣华二采区10...
Aim: The substantia nigra pars reticulata (SNr) constitutes one of the output centers of the basal ganglia, and its abno......
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Validated gradient stability indicating HPLC method for determining Diltiazem Hydrochloride and rela
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
本研究建立了超高效液相色谱-串联质谱法测定人血浆中的7种影响驾驶安全的药物——赛庚啶、西替利嗪、氯苯那敏、艾司唑仑、劳拉西......
A simple and versatile method for the synthesis of 1,5-benzodiazepines from o-phenylenediamine and ketones in the presen......
Validated gradient stability indicating HPLC method for determining Diltiazem Hydrochloride and rela
A stability-indicating liquid chromatographic method has been developed and validated for the determination of Diltiazem......
咪唑安定具有镇静、抗惊厥和顺行性遗忘等作用,其半衰期短,效能强,对血流动力学影响轻微.咪唑安定在麻醉术前用药、门诊短小手术或......
1例64岁男性患者，因突然行走不能，伴头晕，继而人事不清，呼之不应，以“急性缺血性脑血管病”收入院。给予改善循环，营养脑细胞，抗血小板聚......
目的 研究慢性饮酒对雄性大鼠睾丸外周型苯二氮类受体(PBR)和类固醇生成快速调节蛋白(StAR)表达的影响.方法 以不同浓度的乙醇饲......
目的 调查广泛性焦虑症(generalized anxiety disorder,GAD)患者苯二氮卓类药物(benzodiazepine,BZD)使用情况及和首诊处方的关系.......
S-akyl thiobenzoate compounds were designed as famesyltransferase (FTase) inhibitors.An effective synthetic method was e......
A simple and versatile method for the synthesis of 1,5-benzodiazepines from o-phenylenediamine and ketones in the presen......
A series of 3-methoxycarbonylpropoxy-7-(imidazol-4-ylpropinamide)-1, 3-dihydrogen-1-methyl-5-phenyl-2H-1, 4-benzodiazepi......
Electromagnetic fields (EMFs) can interact with biological tissues exerting positive as well as negative effects on cell......
本文就有关苯二氮(艹卓)类的应用情况对1954人作了调研,结果表明:(1)服药率为33%,连续服药一年以上为25.55,(2)应用最多是安定,第......
为探讨氟马西林对诊断及治疗药物中毒所致昏迷患者的有效性及安全性。31例疑苯二氮Zhuo类（BZs)药物中毒昏迷患者以氟马西林0.2mg静......
为了解贵阳市中小学生使用苯二氮Ｚｕｏ类（ｂｅｎｚｏｄｉａｚｅｐｉｎｅ，ＢＺＤ）药品情况，采用整群抽样及单纯随机抽样对贵阳市部分中小学校的２７６１名学生进行了调查，结果显示，使用ＢＺＤ的学......
目的：探讨海洛因与苯二氮Ｚｈｏｕ炎（ＢＺＤ）混合依赖者的临床特征。方法：对近年诊治的５６例洛洛因与ＢＺＤ类混合依赖者的戒断症状进行分析。结果：５６例中有４８例出现......
目的：了解武汉地区中学生使用苯二氮[艹卓]（BZD）类药的现状。方法：采用整群抽样方式，在武汉市7个中心城区，共抽取258个班，采用自行设计的......
目的建立样品前处理方法,通过苯二氮胶体金试纸,实现对保健食品中违法添加苯二氮类化合物的样品进行快速检测。方法结合胶体金......
以邻氯苯甲酰氯及对氯苯胺为原料合成二氢喹唑啉化合物（２），后者水解、经溴乙酰化、乙醇胺化和环合反应合成了抗焦虑药氯恶唑仑，总收率为......
目的比较氟马西尼与纳洛酮抢救苯二氮萆类药物急性中毒的临床疗效。方法选取2012年3月至2015年1月收治的急性苯二氮萆类药物中毒患......
目的:概述苯二氮革类药物的依赖性及其正确合理应用;方法:查阅资料总结苯二氮草类药物依赖性的表现特征和形成因素;结果:苯二氮草......
目的：探讨苯二氮Zhuo类受体拮抗剂－－氟马西尼抗昏迷治疗的临床应用价值。方法：随机将126例急笥苯二氮Zhuo类药物（BZDs）中毒患者分为氟马......
目的：概述苯二氮Zhuo类药物的依赖性及其正确合理应用；方法：查阅资料总结苯二氮Zhuo类药物依赖性的表面特征和形成因素；结果：苯二氮Zhuo......
将３３头泌乳中期荷斯坦奶牛随机分为３组，试验Ⅰ组日粮中添加１．２ｍｇ／ｋｇ的Ｆ８９，试验Ⅱ组日粮中添加２０ｍｇ／ｋｇ的瘤胃素，结果表明：在热应激条件下，Ｆ８９可以提高奶牛的粗饲料......
A series of 3-methoxycarbonylpropoxy-7-(imidazol-4-ylpropinamide)-1,3-dihydrogen-1-methyl-5-phenyl-2H-1,4-benzodiazepin-......
PK11195, a ligand of peripheral-type benzodiazepine receptor can stimulate thealdosterone secretion of isolated adrenal ......
目的：评估临床药师实施干预措施对降低苯二氮革类药用量的效果。方法：临床药师为重复应用苯二氮革类药3个月以上的成年患者制订撤药......
应用^1HNMR技术对一些以[2＋4]环加成方式合成出的苯并二氮杂卓的立体化学进行了研究。利用偶合常数和gNOESY的结果，证明了二氮杂卓七......
目的比较氟马西尼和纳洛酮与相应的急救护理对急性苯二氮类药物中毒患者的临床疗效。方法选择120例苯二氮类药物急性中毒患者,......
目的通过对苯二氮类药物滥用监测数据进行分析，判断吉林地区苯二氮类药物滥用趋势，运用药物滥用的监测手段来反映此类人群各项特......
目的：调查研究苯二氮革类抗焦虑药物的使用现状。方法：随机对150户家庭应用心理卫生调查表、药物依赖性调查表、精神现状检查（PsE）、焦......
Since benzodiazepine/γ-amino butyric acid receptor was found in the spinal cord,there have been many studies to investi......
High- and Low-Rearing Rats Differ in the Brain Excitability Controlled by the Allosteric Benzodiazep
Rearing is an exploratory behavior induced by novelty, such as exposure to an open field. Stimulation of certain brain r......
5mg/kg 苯二氮卓化合物 F89添加于生长期的大鼠日粮中,连续饲喂30d。同对照组相比,平均日摄食量和增重分别提高24.6%和66.9%(P【0.......
Involvement of flumazenil-insensitive benzodiazepine binding site in benzodiazepine-induced anesthes
OBJECTIVE To identify the involvement of flumazenil-insensitive benzodiazepine (BZD) binding site in mediating BZD - ind......
AIM To evaluate the serum levels of endozepine-4, theirrelation with ammonia serum levels, the grading of comaand the se......
１ＩＮＴＲＯＤＵＣＴＩＯＮＩｎｒｅｃｅｎｔｙｅａｒｓ，ｉｔｈａｓｆｏｕｎｄｔｈａｔｂｅｎｚｏｔｈｉａ／ｄｉａｚｅｐｉｎｅｔｒｉｃｙｃｌｉｃｄｅｒｉｖａｔｉｖｅｓａｒｅｐｏｔｅｎｔｉａｌｐｈａｒｍａｃｅｕｔｉｃａｌａｇｅｎｔｓ〔１２〕．Ｔｈｕｓ，ｗｅ.........
Purkinje-neuron-specific down-regulation of p38 protects motoric function from the repeated use of b
Benzodiazepine (BZD) is the most prescribed CNS depressant in America to treat hyper-excitatory disorders such as anxiet......
Benzodiazepines and related benzodiazepine-receptor agonists such as the pyrazolopyrimidinezalepl -on;?the imidazopyridi......
